Reactions analogous to flavin oxygenation have been proposed for enzymes catalyzing the cofactor-independent oxygenation of, for example, urate, 3-hydroxy-4-(1H)quinolones, p-hydroquinone ...

These cofactors, or coenzymes, provide additional functionality that extends considerably the scope of enzyme-catalyzed reactions. Some cofactors (including the iron-porphyrin prosthetic groups of ...

In silico analysis of five industrial microorganisms identifies optimal strains and metabolic engineering strategies for ...

Researchers have identified BbLDH as a critical component for the survival and infectivity of Borrelia burgdorferi, the bacteria responsible for Lyme disease. The fundamental nature of BbLDH lies in ...

Researchers have discovered that an enzyme can serve as an ideal target for developing new therapeutics against Lyme disease, ...

Scientists have discovered that the enzyme BbLDH is crucial for the survival and infectivity of the Lyme disease bacterium ...

The researchers used site-specific mutagenesis to gain new insights into how the cofactor precursor is integrated into the enzyme and how individual amino acids are involved in anchoring and ...