Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Total synthesis has long been a proving ground for advancing chemical thought, pushing ...

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.joc.5c00141.

and then after it cools, you mix in a um, epoxide, which is just a fancy-schmancy name for any simple oxygenated adhesive, right? But then I thought maybe, just maybe, you could raise the ...

The new compound is an inhibitor of soluble epoxide hydrolase (sEH), an enzyme involved in the regulation of several physiological processes, including inflammation and pain response.

Get Instant Summarized Text (Gist) A novel Alzheimer's drug candidate shows promise by reducing inflammation and protecting neurons. It inhibits soluble epoxide hydrolase (sEH), increasing ...

After amines, anhydrides are the second most widely used class of epoxy-curing agents. What sets them apart is their ability to react with both oxirane (epoxide) and secondary hydroxyl groups present ...

Most releases of methyl methacrylate are to the air. It can also evaporate from the soil or water when they are exposed to air. In the air it breaks down into other chemicals (pyruvic acid, methyl ...

This study investigated the hypothesis that inhibiting soluble epoxide hydrolase (sEH), responsible for converting epoxyeicosatrienoic acids to dihydroxyeicosatrienoic acids protects mitochondrial ...