Seven-transmembrane receptors (7TMRs), also known as G protein-couple receptors, are the largest class of transmembrane receptors and a common target for therapeutics. Initially thought to signal ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

Specifically, Auletta highlights the emerging science in stem cell transplants and cell therapies, including treatments like chimeric antigen receptor (CAR) T-cell therapy. He also discussed topics ...

GLP-1 receptor agonists are pharmaceutical treatments primarily for T2D and more recently, obesity. They function by mimicking the action of GLP-1 hormone, which plays a crucial role in ...

Copyright: © 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

Notable findings include DEGs involved in chemokine signaling - particularly the CCL2/CCR2 axis - TGF-β signaling, toll-like receptor (TLR) expression, and key intracellular pathways such as PI3K/Akt, ...

Sweet taste receptors in the heart: A new pathway for cardiac regulation New research shows that the heart can sense sweeteners and can increase the force of heart muscle contraction in response ...

Additionally, their research may explain why high consumption of artificially sweetened beverages is linked to arrhythmogenesis, or an irregular heartbeat. Not only are these sweet taste receptors ...

本报告研究全球与中国市场高纯氧化铝陶瓷球的发展现状及未来发展趋势，分别从生产和消费的角度分析高纯氧化铝陶瓷球的主要生产地区、主要消费地区以及主要的生产商。重点分析全球与中国市场的主要厂商产品特点、产品规格、不同规格产品的价格、产量 ...

12月1日，中国（新疆）自由贸易试验区创新发展研究中心揭牌仪式暨学术交流研讨会议，在新疆大学红湖校区举办。该研究中心由新疆维吾尔自治区商务厅、新疆大学与中国（深圳）综合开发研究院三方携手共建，将打造高水平研究平台，聚焦关键议题，开展 ...

Figure 1. Signal transduction mechanism of EGFR (epidermal growth factor receptor) transactivation by angiotensin II (AngII) in vascular smooth muscle cells leading to vascular remodeling. Please note ...