The new study in The American Journal of Pathology, published by Elsevier ... Idiopathic pulmonary fibrosis (IPF) is a devastating progressive fibrotic lung disease with a median survival of ...

Cysts, fibrosis, and tubular degeneration form the typical triad of pathologies leading to the gradual decline in kidney ...

Good morning! Citigroup in the middle of funding freeze fallout, Ursula von der Leyen offers Trump a “zero-for-zero” tariffs ...

The diagnosis of nonalcoholic steatohepatitis requires histopathologic evaluation because the lesions of parenchymal injury and fibrosis cannot ... lesions in the pathology of NASH, including ...

That's about to change. "This is a major breakthrough in our ability to be able to control the cells that drive fibrosis," said Guy Genin, the Harold and Kathleen Faught Professor of Mechanical ...

of the Department of Pathology and Laboratory Medicine, University of California, San Francisco. Liver fibrosis is known to be the main driver of chronic liver disease as well as a key factor ...

Panelists discuss how distinguishing pre-fibrotic myelofibrosis from other myeloproliferative neoplasms like essential thrombocythemia remains challenging due to overlapping clinical and molecular ...

In a recent study published in the Journal of Cystic Fibrosis, Don Ingber and his group at the Wyss ... Ingber found that the epithelium was the major driver of CF lung pathology. Like patient lungs, ...

The findings emphasize the importance of exosomal lncRNAs, which function as molecular regulators in kidney pathology and hold ... ultimately resulting in renal fibrosis and organ failure.

More information: Margaret A.T. Freeberg et al, Piezo2 Is a Key Mechanoreceptor in Lung Fibrosis that Drives Myofibroblast Differentiation, The American Journal of Pathology (2025). DOI ...

Piezo2 is increased in idiopathic pulmonary fibrosis (IPF). Immunohistochemistry of nonfibrotic (left) and IPF (right) lung tissue demonstrating that Piezo2 (brown staining) is strongly present in ...