The following is a summary of “Higher doses of fluconazole are needed to ensure target attainment in critically ill adults on continuous Veno-venous hemodialysis,” published in the February 2025 issue ...

Fluconazole 2mg/mL; soln for IV infusion. Fluconazole is a highly selective inhibitor of fungal CYP450 dependent enzyme lanosterol 14-α-demethylase. This enzyme functions to convert lanosterol to ...

Peak fluconazole concentrations of 16–32 µg/ml were reached in all patients. Mean concentrations above 16 µg/ml were maintained for 17.0 ± 8.0 h at an ultrafiltration rate of 1,000 ml/h, ...

Effective from January 1, 2001, standard fluconazole prophylaxis for all VLBW infants has been instituted in our NICU: thus, a comparison was also made among the 2 different periods (July 1997 ...