Feb. 7, 2025 — A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 ...

Delhi Chief Minister Rekha Gupta issued several directives including one for formation of a monitoring cell for regular updates on ongoing infrastructure work in the city, officials said on Saturday.

During atherogenesis, macrophages turn into foam cells by engulfing lipids present within the atheroma plaques. The shift of foam cells toward proinflammatory or anti-inflammatory phenotypes, a ...

Herein, we report facile bimetallic Fe/Co-MOF (iron/cobalt–metal organic framework) nanospindles deposited onto nickel foam as an electrocatalyst for direct copper cell applications. The detailed ...

Our results demonstrate an important role for filopodia and the regulating protein—espin in confined cell migration and shed new light on cytoskeletal mechanisms underlying metastasis. Espin induces ...

Moreover, Cryptococcus- and Mycobacterium-infected macrophages accumulated triglycerides in different ways. Collectively, the data show that the molecular events underlying foam cell formation are ...

those cells may then need a secondary inflammatory process to drive tumor formation. Knowledge about what pushes tumors to develop could be used for comprehensive personalized risk assessment ...

In fact, mutations in condensin structure can result in severe chromosome segregation defects and lead to cell death, cancer formation, or rare developmental disorders called 'condensinopathies.' ...

Iron deficiency often develops gradually, making it difficult to recognize early symptoms. Some common signs include: Fatigue and Weakness – Due to reduced oxygen transport. Pale Skin and ...

When foam cells are in a tumour environment, this also activates mechanisms that make tumours more aggressive and worsen prospects for survival. They begin to release signal substances that facilitate ...