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IL-19:胶质母细胞瘤治疗的新兴有前景靶点
研究结论和讨论部分指出,IL-19 是一个有前景的治疗诊断靶点,IL-19 抗体疗法可与 TMZ 治疗相结合,有望改善整体治疗效果。该疗法能够直接靶向异常的细胞因子信号,对免疫抑制的 M2 巨噬细胞和 TMZ 耐药的 GBM 微环境中的肿瘤侵袭性产生更有针对性的影响。同时,CHOL-PEG-SPIO-IL19 纳米颗粒的开发进一步凸显了 IL-19 作为 GBM ...
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