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有氧运动激活瘦素 / LepR/GSK-3β 通路缓解阿尔茨海默病神经炎症及记忆 ...
同时,探究为期 12 周的跑步机运动对瘦素(leptin)/ 瘦素受体(LepR)/ 糖原合成酶激酶 - 3β(GSK-3β)信号通路以及记忆的影响。研究发现,高脂饮食喂养的小鼠体重增加,瘦素抵抗的标志物,如细胞因子信号转导抑制因子 3(SOCS3)、蛋白酪氨酸磷酸酶 1B(PTP1B ...
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