编者按：5月17日是世界高血压日。高血压素有"沉默杀手"之称，其危险性在于症状的隐匿性——患者往往在通过常规血压检测确诊前毫无察觉。此外，这种悄无声息的疾病会持续侵蚀心、脑、肾等重要器官，最终可能引发心梗、卒中、肾衰竭等致命后果。随着RNA干扰技术和 ...

One of the main goals in the prevention of cardiovascular disorders is to maintain low-density lipoprotein cholesterol (LDL-C) at consistently low levels to ensure long-term cardiovascular protection.

Reported positive initial data from the Heart-2 Phase 1b clinical trial of VERVE-102 demonstrating dose-dependent decreases in blood LDL-C and PCSK9< ...

Detailed price information for Arbutus Biopharma Corp (ABUS-Q) from The Globe and Mail including charting and trades.

Operating and Financial ResultsAxiomer™ ADAR-mediated RNA editing pipeline advancing across liver and CNS programs, with CTA filing on track for Q2 2025 for lead program AX-0810 targeting NTCP for ...

“Our RestorAATion-2 trial of WVE-006, a subcutaneously-dosed GalNAc-conjugated RNA editing oligonucleotide, continues to ...

LONDON, May 07, 2025 (GLOBE NEWSWIRE) -- e-therapeutics plc, a company integrating computational power and biological data to discover life-transforming RNAi medicines, today announced it will present ...

研究揭示结直肠癌中遗传因素与肿瘤内微生物群的相互作用机制，为精准治疗提供新思路。通过检测rs2355016 SNP和福氏梭菌水平，可识别高风险患者群体。

This downregulation may increase the presence of Gal-GalNAc on the surface of tumor cells. The increased Gal-GalNAc interacts with Fap2, enhancing the adhesion and invasion of F. nucleatum ...

DSPE-PEG-GalNAc（磷脂-聚乙二醇-N-乙酰半乳糖胺）由三个功能模块组成：疏水性的磷脂DSPE可嵌入脂质体或脂质纳米颗粒中作为锚定基团，亲水性的PEG链提供空间位阻和长循环能力，末端连接的GalNAc（N-乙酰半乳糖胺）可特异性识别肝细胞表面的ASGPR受体，实现靶向 ...

Shandong Key Laboratory of Glycoscience and Glycotherapeutics, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, P. R. China Key Laboratory of Marine Drugs, Ministry of ...