为探究奥拉帕利治疗 eligibility，研究人员开展 BRCA 1/2 突变乳腺癌研究，约 1/3 患者或可受益。 背景：携带生殖系 BRCA 1/2 致病性变异的人表皮生长因子受体 2（HER2）阴性可手术乳腺癌（BC）患者，或许能从辅助奥拉帕利治疗中获益。然而，目前缺乏新辅助化疗 ...

M utations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of ...

People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of them doesn't function. For cancer-suppressor genes like BRCA1 ...