iPS cardiomyocytes are designed for transplants for patients with severe heart failure who have no effective alternatives other than heart transplant or venticular assist devices. The team hopes ...

Guangdong Engineering & Technology Research Center for Disease-Model Animals, Laboratory Animal Center, Sun Yat-sen University, Guangzhou, China. (T.W., T.H., H.R., C ...

The "iPS heart" displayed on April 2 with a diameter of approximately 3.5 centimeters was built from iPS cells differentiated into cardiomyocytes -- the cells that generate a heartbeat -- and ...

iPSCs are reprogrammed from adult stem cells to become any cell type in the body – in this case, cardiomyocytes in the heart. Arrhythmia or tumor growth can occur when pluripotent stem cells ...

The number and function of muscle cells in the heart differ, too. Women’s hearts have more cardiomyocytes than men, and their fuel tends to be more fatty acids as opposed to the sugars that male ...

Shenzhen Key Laboratory of Smart Healthcare Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Department of Biomedical Engineering, Southern University of Science and ...

Cardiomyocytes from Alpk3 K201X mice display reduced resting sarcomere length with prolonged relaxation：分离 Alpk3 K201X 小鼠的心肌细胞研究发现，与野生型相比，杂合子和纯合子心肌细胞的基础肌节长度显著缩短，舒张 90% 所需时间延长，纯合子细胞收缩持续时间也延长。 Reduced ...

Sharma spent years developing methods to turn induced pluripotent stem cells (iPSC) into either cardiomyocytes or vascular endothelial cells. 2 However, he noticed that the cells never quite matured ...

Objective: Brain-derived neurotrophic factor (BDNF) and its receptor TrkB-T1 were recently found to be expressed in cardiomyocytes. However, the functional role of cardiomyocyte-derived BDNF in heart ...

Department of Physical Therapy, College of Medicine, National Cheng Kung University, Tainan, Taiwan Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan ...