结果发现 NMN 通过激活 H4K16ac-Hmgb1-Fyn-PLD 信号通路促进 FGSC 增殖，为生殖医学提供了新的治疗靶点。 在生命的长河中，生育是延续人类种族的关键环节，而女性的生殖健康则在其中扮演着至关重要的角色。近年来，不孕不育的发生率不断攀升，这一现象引发了 ...

1 The College of Life Sciences, Northwest University, Xi’an, Shaanxi, China 2 Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi’an, Shaanxi, China High-mobility group ...

干旱严重威胁粮食安全，水稻生产耗水且易受干旱胁迫影响。研究人员开展了对比旱稻和灌溉稻根系发育的研究，通过表型、细胞学及空间转录组分析，发现 HMGB1 是旱稻根系发育和增强抗旱性的关键基因，为培育抗旱水稻提供了遗传资源。 干旱严重威胁粮食 ...

Briefly, culture supernatant was collected and centrifuged to remove cell debris. Subsequently, the extracellular HMGB1 was quantified using an enzyme-linked immunosorbent assay (ELISA) kits (R&D ...

A noninvasive clinicopathologic and gene expression profiling (CP-GEP)–based tool, the Merlin assay, shows promise for identifying recurrence risks in patients with early-stage melanoma who do ...

Biocartis announced the launch of its real-time quantitative polymerase chain reaction assay to detect POLE and POLD1 mutations in endometrial cancer. Biocartis has launched a fully automated, ...