Autophagy is a highly conserved lysosomal degradation system that involves the creation of autophagosomes, which eventually fuse with lysosomes and breakdown misfolded proteins and damaged organelles ...

为探究肿瘤细胞调节共刺激分子的机制，南方医科大学南方医院研究人员开展 ATF4 对 CD8? T 细胞功能影响的研究，发现 ATF4 可削弱 CD58 表达，为肿瘤免疫治疗提供新方向。 肿瘤免疫治疗近年来发展迅速，就像一场与肿瘤细胞的激烈 “战斗”。免疫系统中的 CD8?

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ADPN impeded cardiac edema and promoted lymphangiogenesis by increasing macrophage infiltration post-infarction. Adipocyte-derived ADPN promoted M2 polarization and sustained mitochondrial quality via ...