In this article we give an overview of RNA-based HPV diagnostics and the role of E6/E7 mRNA detection as a predictive marker for the development of cervical carcinoma. HPV E6/E7 mRNA testing for ...

The researchers can model this either by editing the genes themselves or inhibiting their expression with HPV E6 and E7 oncoproteins. These two oncoproteins help drive HPV-associated cancers by ...

The E6 and E7 proteins are key oncogenes in the development of HPV-associated tumors, and therapeutic vaccines targeting HPV16 E6 and E7 tumor-specific antigens -- such as Vvax001 -- "represent an ...

Enzo’s innovations are changing the story of HPV. The FLOWSCRIPT® Assay employs a novel, flow cytometry-based, in situ hybridization technique, utilizing a cocktail of probes specific to multiple ...

Gen-Probe is currently developing the APTIMA HPV Assay, targeting E6/E7 mRNA from 14 carcinogenic HPV genotypes. A prototype of this assay was evaluated recently in 536 women with histological ...