Ewa Moric-Janiszewska, Ph.D.; Grazyna Markiewicz-Loskot M.D. Ph.D.; Maria Loskot M.D.; Ludmila Weglarz; Andrzej Hollek M.Sc.; Leslaw Szydlowski M.D.

Induced pluripotent stem cells (iPSCs) originate from the reprogramming of adult somatic cells using four Yamanaka transcription factors. Since their discovery, the stem cell (SC) field achieved ...

减少成本和时间：通过减少对昂贵的Thorough QT研究的需求，CiPA有望降低药物开发的成本和时间，同时提高患者获得安全有效治疗的机会。 爱思益普电生理团队构建了相关离子通道的7种（hERG，Nav1.5，Cav1.2，Nav1.5-Late，Kv4.3，Kir2.1，IKs）和hiPSC-CMs动作电位膜片钳检测 ...

From carrying potentially pathogenic genes to severe clinical phenotypes, the basic research in the inherited cardiac ion channel disease such as long QT syndrome (LQTS) has been a significant ...

This important study finds that the location of recruitment of a protein kinase to an ion channel can change the complement of residues modified, leading to channel function being altered by a ...

A clone of Media Player Classic reimplemented in Qt. Media Player Classic Home Cinema (mpc-hc) is considered by many to be the quintessential media player for the Windows desktop. Media Player Classic ...

Cells are surrounded by a membrane that separates the outside of the cell from its inside. Proteins called ion channels are embedded within this membrane and allow charged ions to move in and out of ...