Nephronophthisis (NPH) is a recessive cystic kidney disease responsible for 10% to 20% of pediatric end-stage renal disease cases. NPHP1 (nephrocystin 1) is the most frequently implicated among over ...

Among these signals, the TGF-β and HIPPO pathways are critical, functioning as tumor suppressors and regulating liver development and regeneration. The review focuses on these pathways' interplay ...

SAN MATEO, Calif., March 12, 2025 /PRNewswire/ -- Vivace Therapeutics, Inc., a small molecule discovery and development company developing first-in-class cancer therapies targeting the Hippo pathway, ...