Disorders of surfactant protein biology cause dysfunction of alveolar type 2 cells and can lead to interstitial lung disease. This study describes the development of genetically manipulable, mature ...

In summary, we demonstrate the development of a novel alveolar organoid model and use it to identify effectors of SFTPC maturation ... which can self-renew and differentiate to alveolar type 1 cells, ...

Signet’s organoid models, derived from real-world cancer genomics data, can closely mimic human biology in 3D tissues to identify novel targets and evaluate drug efficacy with greater clinical ...

When Homo sapiens appeared some 300,000 years ago, at least six other human species already shared the planet. Here, in the studio of paleoartist John Gurche, are model representations of those ...

On January 14, hippies and other counterculture participants swarmed to the polo grounds in San Francisco’s Golden Gate Park in a gathering called the Human Be-In. Timothy Leary advised ...

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract that affects an estimated 2.4 to 3.1 million people in the US alone. Despite decades of research, ...

Tongue cancer organoids reveal secrets of chemotherapy resistance A novel patient-derived organoid library helps researchers identify promising drug targets, including autophagy and cholesterol ...

In our experimental protocol, the BEAS-2B normal human lung epithelial cells and LUAD cell lines (A549, H1650,H1975,H1299) were obtained from the Cell Resource Center of the Shanghai Institute for ...

HMPV Infection Symptoms: Human metapneumovirus, also known as HMPV, is a severe respiratory illness caused by a virus that was first identified in 2001 by Dutch researchers. This virus primarily ...

HMPV may not be as severe as COVID, but it can still affect the lungs, causing respiratory issues, especially in vulnerable populations. Amid the recent Human Metapneumovirus (HMPV) outbreak in ...