People who eat sugar substitutes in an effort to lose or control their weight could be making matters worse, if recently published research in the journal Nature Metabolism is anything to go ...

This review highlights the key areas of research in the hypothalamic control of appetite. The hypothalamus consists of several nuclei that integrate peripheral signals, such as adiposity and ...

Within the hypothalamus, the brain’s hub for all our basic needs, two groups of neurons influence how we respond during isolation vs. social interactions. Connecting with others, ten ...

Compared to sugar, consuming sucralose—a widely used sugar substitute—increases activity in the hypothalamus, a brain region that regulates appetite and body weight, according to new USC research.

Many people use sugar substitutes so that they can taste the sweet stuff without consuming as many calories. It's estimated ...

Rhythm is evaluating setmelanotide in a global Phase 3 trial in patients with acquired hypothalamic obesity, with topline data on track to be disclosed in the second quarter of 2025.