The data to be presented encompasses five of the company’s novel drug candidates: BCR-ABL tyrosine kinase inhibitor olverembatinib (HQP1351), Bcl-2 inhibitor lisaftoclax (APG-2575), FAK/ALK/ROS1 ...

He was the President of Nagpur IAP Branch. IAP, Nagpur and has won all the prizes at State and National level for the year 2013. IAP Maharashtra, called as MahaIAP is a robust branch with more ...

Some of these dead cells will have died by a highly controlled process known as apoptosis. These so-called apoptotic cells display signals on their surface that nearby healthy cells recognize. This ...

which induces the damage of cell target during apoptosis and is challenging to be inhibited by regular inhibitors of apoptosis proteins (IAP). It has been found that CARPs interact specifically with ...

Here we will review and discuss the available experimental evidence on how NK cells kill target cells, with a special focus on the different cell death modalities that have been found to be activated ...

However, it remains unclear if viral infection has any impact on the N-end rule pathway. Here, using a picorna-like virus as a model, we found that viral infection promoted the accumulation of caspase ...