Lirum Therapeutics, Inc. (“Lirum”), an innovative clinical-stage biopharmaceutical company focused on the treatment of debilitating diseases, announced today the presentation of ...

DelveInsight’s “TEPEZZA Market Size, Forecast, and Market Insight Report” highlights the details around TEPEZZA, an insulin-like Growth Factor-1 receptor (IGF-1R) inhibitor. The report ...

Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.

The Basal Ganglia (BG) are a group of brain nuclei involved in motor control. Their cellular composition, interactions and connectivity still being elucidated. The focus of the lab is studying the ...

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

[54] Finally, signaling pathways downstream of EGFR may become activated as a means of inducing tumor growth to counteract anti-tumor drug effects. Good evidence exists for the use of anti-EGF ...

Insulin-like growth factor (IGF) 1 is a member of a family that is ... Upon binding to the GH receptor, this hormone activates signaling pathways that lead to transcriptional activation or ...

Peptide mimics must also be designed to adopt structures of the corresponding ligand or receptor to function as effective inhibitors of signaling pathways. Combining minimal doses of ...