Scientists at King’s College London have developed an innovative IgE antibody therapy that activates the immune system to ...

The properties of the different IgG isotypes should be considered in developing ... but is likely to also apply for IgG2, IgG3, IgE and IgM. The evolutionary advantage of functional monovalency ...

Type I allergy, an IgE antibody triggered hypersensitivity disease, represents a common public health problem affecting about one third of the world´s population. Upon exposure to allergens, IgE ...

HER2 is responsible for cancer growth and is the target of existing therapies, such as the most commonly used type of antibodies, IgG. However, this treatment is not always effective in some patients.

The team from King’s College London, UK, investigated a different antibody type, IgE, which activates the patient’s immune system in different ways than IgG. As they act on different immune cells to ...

Targeting IgE with a protease such as S‑8484 offers ... S-1117 is a novel engineered Fc-fused pan-IgG protease targeting IgG autoantibodies, and S-4321 is a non-depleting bifunctional PD ...

Tumours, such as some breast and ovarian cancers, can express the marker HER2. HER2 is responsible for cancer growth and is the target of existing therapies, such as the most commonly used type of ...

An antibody discovery platform revealed more than 60 monoclonal antibodies specific to patients with alpha-gal syndrome, ...

There were no clinically significant reductions in other immunoglobulins including IgG 3, IgA, IgE, or IgM compared to baseline. Based upon the rapid and deep reductions of total IgG observed with ...

Serum was stored at −80°C. IgM, IgD, IgA, IgG, IgG1, 2, 3, and 4, and total IgE were measured. Results: The following immunoglobulins were significantly (p⩽0.05) altered after the race: IgD, ...