The deal with startup Dren Bio hands Sanofi a so-called myeloid cell engager that would compete with an array of programs ...

Orphan Drug Designation follows positive Phase 1 data presented at the 12th International Workshop on Waldenström ...

CD19-targeted CAR T cells have transformed the management of patients with relapsed and/or refractory large B cell lymphoma, and these therapies are increasingly being administered as earlier-line ...

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) characterized by a dominant antimyeloperoxidase (MPO) response mediated by CD27+IgM+ B cells exhibited persistent memory-like ...

In response to T-cell-dependent antigens, mature B cells in the secondary lymphoid organs are stimulated to form germinal centers (GCs), which are histological structures deputed to antibody affinity ...

Upregulated STAT1 and IRF9 within pSS B cells were associated to extraglandular manifestations, high anti-SS-A and anti-SS-B autoantibodies, high anti-nuclear antibody titers (ANA) and rheumatoid ...

28 As they are involved in the neutralisation of circulating endotoxin, EndoCAb immunoglobulins are typically depleted in response to an acute LPS exposure, but eventually rise due to the B-cell ...

When your doctor talks to you about your B-cell lymphoma ... If you have this cancer, you make too much of a protein called immunoglobulin M (IgM). You may get symptoms such as bleeding easily ...

为探究 B 淋巴细胞产生的 IgM 对视网膜衰老的影响，研究人员开展相关研究。结果发现缺乏分泌型 IgM 会加速视网膜衰老退化。这一成果为理解眼部衰老机制和开发相关免疫干预措施提供新思路，值得科研读者一读。 在我们的身体里，眼睛就像一台精密的 “光学 ...

为探究 B 淋巴细胞产生的 IgM 在眼部正常生理过程中的作用，作者[第一作者单位] 研究人员开展相关研究。结果发现缺乏分泌型 IgM 会加剧视网膜衰老退化。该研究为理解眼部衰老及相关疾病提供新视角，推荐科研读者阅读。 探索 IgM 在眼部健康中的奥秘 ...