At the core of TEMs are tetraspanins engaging in direct protein–protein interactions with themselves and other proteins, including the immunoglobulin superfamily members EWI-2 and EWI-F ...

Sialic acid–binding immunoglobulin-like lectins (Siglecs) are cell-surface transmembrane receptors that are differentially expressed on immune cells (Läubli and Varki, 2020). They play critical roles ...