Background: COL4As, a group of six homologous genes that encode the type IV collagen α chains (α1-α6), have been identified as the main components of the collagen network in brain basement membranes.

结果发现 FAP+ CAFs 可诱导巨噬细胞向 M2 样极化，且 FN1-Integrin α5β1 轴或可成治疗靶点，意义重大。 表达成纤维细胞激活蛋白（FAP + ）的癌相关成纤维细胞（cancer-associated fibroblasts，CAFs）是乳腺癌微环境的关键调节因子，但其免疫调节机制尚不清楚。通过单细胞 ...