This important computational study investigates homeostatic plasticity mechanisms that neurons may employ to achieve and maintain stable target activity patterns. The work extends previous analyses of ...

We have shown that intrinsic excitability changes after induction of synaptic plasticity. We have shown that intracellular calcium dynamics also changes after induction of synaptic plasticity. We ...

This capacity for cellular plasticity is critical for normal embryonic ... either as a result of cell-intrinsic genetic and epigenetic programming or because of the effect of the tissue environment.