Given their earlier finding that IL-3 acts indirectly on CTL, the team sought to pinpoint the intermediary cells. Using flow cytometry, they isolated splenocyte populations and observed that basophils ...

C. Ohnmacht et al., “Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths,” Immunity, 33:364-74, 2010. Free F1000 Evaluation Basophils were deemed critical in ...

The basophil activation test (BAT) is not a primary diagnostic tool; it is a test complementary to the skin test and quantification of allergen-specific IgE. The BAT is currently mostly applied in ...