衣康酸是一种天然存在的物质，通过与免疫系统相互作用而具有抗炎作用。然而，衣康酸的弱点是它不容易穿透细胞。Majer团队花了几年时间开发一种治疗秃头的药物，通过开发基于衣康酸衍生物的前体药物克服了这一障碍，其中前体药物是一种仅在体内转化为活性药物的化合物。

The results of their study, recently published in the Journal of Medicinal Chemistry, confirm the efficacy of a series of prodrugs based on derivatives of itaconic acid, simply referred to as ...

The results of their study, recently published in the Journal of Medicinal Chemistry, confirm the efficacy of a series of prodrugs based on derivatives of itaconic acid, simply referred to as ...

A research group, led by Dr. Pavel Majer from IOCB Prague, in collaboration with the laboratories of Barbara Slusher and Louis Garza at Johns Hopkins University, has developed a compound that could ...

THE observation reported in the present note relates to an Aspergillus with yellow- to ochraceous-eoloured conidia. The mould does not appear to correspond entirely with any published description.

Researchers have developed a compound that could potentially treat the autoimmune disorder alopecia areata, which causes hair loss leading to the formation of bald patches. The results confirm the ...

By integrating gene editing, pathway reconstruction, and dynamic regulation, microbial platforms have achieved enhanced biosynthesis of key organic acids such as pyruvate, lactic acid, and succinic ...

Laryngopharyngeal reflux is the medical term for acid that reaches the throat because of reflux. However, changes to the tongue are an uncommon symptom. It is not common for acid reflux to affect ...

Graduate Institute of Environmental Engineering, National Central University, Taoyuan 32001, Taiwan (R.O.C.) Department of Chemical and Materials Engineering ...