Could an arthritis drug unlock lasting relief from epilepsy and seizures? Promising results in mice
A drug typically prescribed for arthritis halts brain-damaging seizures in mice that have a condition like epilepsy, ...
Nature14y
The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival
11 xenograft mouse model, accompanied with inhibition of phospho-FGFR3, phospho-JAK2, phospho-STAT3 and Cyclin D2 levels. In sum, AZD1480 blocks proliferation, survival, FGFR3 and JAK/STAT3 ...
Researchers find possible link between medication and unexpected blood clots
Why do medications that are supposed to help patients with chronic inflammatory diseases sometimes lead to blood clots?