The brain disease model of addiction has dominated public and scientific discourse on addiction (termed substance use disorder [SUD] in the DSM-5) over the past 3 decades. The model framed addiction ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

Host cells activate cell death pathways in response to bacterial manipulation of innate immune signalling, but the molecular ...

The evidence is convincing in terms of the soundness of the theoretical projections and the impact that accounting for group sizes may have on inferences from surveillance data. However, it has not ...

Department of Physiology, State Key Laboratory of Common Mechanism Research for Major Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Basic Medical ...

If you think you found a bug, feel free to open an issue. Focused suggestions and requests can also be opened as issues. Before opening a pull request, start an issue or a discussion on the topic, ...

A little bit of Victorian London history in Steven Knight's new Disney+/Hulu show.

Genie.jl is the backbone of the Genie Framework, which provides a streamlined and efficient workflow for developing modern web applications. It builds on Julia's strengths (high-level, ...

This is an outstanding new method using base editor technology for introducing precise mutations in zebrafish and medaka vertebrate model systems. The approach is some of the strongest evidence to ...

The data were then fitted to a structural equation model to examine two cross-lagged effects. Conclusion: These results provide robust evidence that the relationship between cognition and depressive ...

Obesity is one of the leading causes of preventable death worldwide. Circadian rhythms are known to control both sleep timing and energy homeostasis, and disruptions in circadian rhythms have been ...