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17 天
Chalcone-9:一种靶向 JAK-STAT 通路的三阴性乳腺癌新型潜在治疗药物
结果显示 Chalcone-9 能抑制 JAK-STAT 通路、诱导癌细胞凋亡 ... 分别从蛋白质和 mRNA 水平分析其对 JAK1、JAK2、STAT1 和 STAT3 激活及下游基因表达的影响;利用计算机辅助分子对接分析(in silico molecular docking)探究 Chalcone-9 与 JAK1 和 JAK2 的相互作用;借助划痕愈合实验 ...
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