Figure 1: Representative images of the induction of autophagy and the outcome of its suppression. Figure 2: The role of autophagy in development and differentiation in mammals.

近日，南方科技大学生命科学学院神经生物学系副教授赵燕课题组在国际学术期刊 Autophagy 上发表了题为“ATG2A acts as a tether to regulate autophagosome-lysosome fusion in neural cells”的研究论文，揭示了 ATG2A 在神经细胞中通过结合 SNARE 膜融合复合物等分子，调控自噬小体和溶酶体的融合过程。 巨自噬（以 ...

Sichuan Key Medical Laboratory of New Drug Discovery and Drugability Evaluation, Luzhou Key Laboratory of Activity Screening and Druggability Evaluation for Chinese Materia Medica, School of Pharmacy, ...

Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China ...

Acute stress increased autophagy markers in the lateral habenula, as measured by increased LC3 puncta, decreased p62 protein levels, and higher autophagosome counts under electron microscopy.

研究采用Western blotting、线粒体分离技术和RNA干扰等核心方法，在PK-15细胞模型中探究了FMDV感染与线粒体自噬的时空动态。通过构建GFP-LC3转染体系结合免疫荧光，系统分析了HSP60缺失条件下Drp1磷酸化修饰及Parkin转位的分子事件。 在"Parkin依赖性线粒体自噬被FMDV ...