"In the amygdala, the gene Stat3 is involved in the regulation of blood pressure and possibly plays a role in blood pressure elevation in response to chronic stress. It might also be involved in ...

为探究 Clusterin 在 LPS 诱导肝损伤中的作用及机制，庆熙大学研究人员开展相关研究，发现 Clusterin 可抑制 NLRP3 炎症小体和 STAT3 信号通路来保护肝脏。该研究为炎症性肝病治疗提供新靶点，值得科研读者一读。 在肝脏疾病的研究领域，炎症反应就像一个隐藏在 ...

SEE ALSO: Get the latest forecast from the Storm Alert Team All LPS activities are also canceled, the district said. LPS said it would continue to monitor the conditions for Thursday.

This valuable study presents a screening pipeline (SPICE) for detecting DNA motif spacing preferences between TF partners. SPICE predicts previously known composite elements, but experiments to ...

Meanwhile, the generation of NO and the mRNA and protein expression levels of IL-1β, IL-6, and TNF-α were all dramatically decreased in LPS-stimulated RAW264.7 macrophages after treatment with WSGP.

However, its role in acute liver injury is unknown. In this study, we evaluated the effect of DY131 on lipopolysaccharide (LPS)-induced liver injury. Mice were pretreated with DY131 through ...

Despite existing evidence for tuning of innate immunity to different classes of bacteria, the molecular mechanisms used by macrophages to tailor inflammatory responses to specific pathogens remain ...

Because AKBA (see structure in Fig. 1A) has been used to alleviate various inflammatory diseases, we hypothesized that it would inhibit STAT3 activation. We tested this hypothesis using a MM cell line ...