为探究 Clusterin 在 LPS 诱导肝损伤中的作用及机制,庆熙大学研究人员开展相关研究,发现 Clusterin 可抑制 NLRP3 炎症小体和 STAT3 信号通路来保护肝脏。该研究为炎症性肝病治疗提供新靶点,值得科研读者一读。 在肝脏疾病的研究领域,炎症反应就像一个隐藏在 ...
The mTOR pathway is activated in phagocytes in response to bacterial infection or following exposure to lipopolysaccharide (LPS). Unexpectedly ... of transcription 3 (STAT3), which is necessary ...
"In the amygdala, the gene Stat3 is involved in the regulation of blood pressure and possibly plays a role in blood pressure elevation in response to chronic stress. It might also be involved in ...