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irCLIP-RNP 与 Re-CLIP:解锁 RNA 上动态蛋白质组装的神秘面纱,助力攻克 ...
为探究 RNA 上多蛋白组装体的性质和动态变化,研究人员开展 irCLIP-RNP 和 Re-CLIP 技术相关研究。irCLIP-RNP 揭示了 RNA 上多聚体蛋白组装模式及动态重塑,Re-CLIP 确认了蛋白结合关系。这为研究活细胞中 RNA - 蛋白组装提供了新框架。 RNA 结合蛋白(RBPs)调控着包括 RNA ...
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