[25] The benefit of the losartan-based strategy may have been ... especially in combination treatment. Thiazid and thiazide-like diuretics lower BP by a complex series of mechanisms, such as ...

[5] We addressed the following research questions: How efficacious and safe is losartan, given as mono-therapy or in combination with hydrochloro-thiazide, in typical, unselected patients with a ...

Following reports linking thiazide diuretics with increased biliary cholesterol saturation, it has been postulated that these drugs increase the risk of gallstone development. Leitzmann and ...