A new study shows that dysfunction of lysosomes can cause leakage of toxic substances within brain cells, contributing to ...

Our generation is probably the one that will live the longest. Life expectancy is increasing all the time, and for a long ...

Evidence suggests that in Parkinson’s disease, a breakdown in lysosomal function allows lipids to build up within cells. Variants of the GBA1 gene, the strongest genetic risk factor for sporadic PD, ...

A new set of genes that contribute to Parkinson’s disease risk has been identified.

Zevra Therapeutics, Inc. (NasdaqGS: ZVRA) (Zevra, or the Company), a commercial-stage company focused on providing therapies for people living with rare disease, today announces the publication of ...

NU-9 targets a shared underlying mechanism found in various neurodegenerative diseases. A new study from Northwestern University reports that NU-9, an experimental small-molecule drug currently ...

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged ...

The STING protein, known for helping cells fight viral infections by generating inflammation, also appears to function as a quality control sensor for organelles that serve as cellular waste disposal ...

Parkinson's disease is the second most common neurodegenerative disease in the world... | Genetics And Genomics ...

A longstanding mystery in Parkinson's disease research has been why some individuals carrying pathogenic variants that increase their risk of PD go on to develop the disease, while others who also ...

Researchers have long wondered why some people with high-risk Parkinson’s gene variants develop the disease while others ...

该篇题为"The autophagy protein ATG-9 regulates lysosome function and integrity"的文章于2025年4月9日发表在Journal of Cell Biology上。 ATG-9是定位于30-60 nm囊泡上的蛋白 ...