Proteases that are resident in, or released from, the endolysosomal system of leukocytes have important functions in the immune response. Lysosome-related organelles (LROs) or granules are the ...

What do cells do when they are “hungry”? Eukaryotic cells cope with starving conditions by eating their own components, a process called autophagy. Aa Aa Aa Normally, when you are hungry you ...

The team also ran experiments to confirm that the protein is essential for moving fats out of lysosomes and that certain parts of Spns1 are crucial for its function.