Additionally, the cellular recycling plants—called lysosomes—were missing key digestive enzymes responsible for breaking down waste products, the scientists found. "These vesicles can't reach ...

School of Chemistry and Chemical Engineering, Hunan Key Laboratory for the Design and Application of Actinide Complexes, University of South China, 28 Changsheng West Road, Hengyang, Hunan 421001, P.

Suppressing KCTD20 in both the organoids and mice prevented glutamate from triggering tau accumulation and neurodegeneration. Further experiments showed that blocking this gene’s activity activated ...

Tumor marker blood tests may help inform various aspects of cancer care, including diagnosis, staging, treatment planning, and outlook. However, they’re often not the only diagnostic tests used.

However, tumor marker tests aren’t the only tools they’ll use in cancer care. Other testing techniques will help provide a more comprehensive look at your type of cancer. Regular cells may ...

This month's cover highlights the article Natural variations of adolescent neurogenesis and anxiety predict the hierarchical status of adult inbred mice by Nicolas Toni, Thomas Larrieu and colleagues.

Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea Department of Biosystems and Bioengineering, KRIBB School of Biotechnology, ...

Lysosome-related organelles (LROs) or granules are the main protease storage and processing organelles of the endolysosomal system. The range of proteases present in LROs is cell-type specific.

Obesity is one of the more prevalent diseases, which results in energy imbalance within metabolic tissues and lysosome dysfunction. Less frequent diseases include Niemann-Pick type C (NPC) and Gaucher ...

As the primary adenosine triphosphate-generating organelles, mitochondria are well-known regulators of stem cell fate decisions, yet it is now becoming apparent that additional organelles such as the ...