Eight metastasis-suppressor genes have been confirmed so far. They affect many aspects of signal transduction, including pathways that are involved in invasion, growth-factor-receptor signalling ...

The World Bank’s new mission is to end extreme poverty and boost shared prosperity on a livable planet. The "Poverty, Prosperity, and Planet. Pathways Out of the Polycrisis" report evaluates progress ...

Angiotensin II (AngII) is implicated in promoting atrial remodeling and inflammation. However, the exact pathways through which AngII exacerbates AF are still not fully defined. This study explores ...

We're living through a big moment in spaceflight history. With the launch of Intuitive Machines' Athena spacecraft atop a SpaceX Falcon 9 rocket last night (Feb. 27), three lunar landers are ...

CAPE TOWN, February 28, 2025 — A new World Bank report titled “Driving Inclusive Growth in South Africa: Quick Wins with Competitive Markets and Efficient Institutions” asserts that a robust economic ...

Genomic sequencing endeavors have revealed extensive alterations in key signaling pathways that regulate cellular proliferation and survival. Initiatives to engineer therapies targeting these ...

Rather, we found that TIR-1 functions cell-autonomously to regulate each of the seemingly opposite processes through distinct interactions with two MAP kinase pathways. On one side of the injury, ...

Injury-induced (Wallerian) axonal degeneration is regulated via the opposing actions of pro-degenerative factors such as SARM1 and a MAPK signal and pro-survival factors, the most important of which ...