MDM2 degradation was not observed with the clinically relevant or high dose of DS ... as indicated by cleaved caspase-3 (CC-3) staining, following an SD of KT-253 at 1 or 3 mg/kg. In contrast, neither ...

The best carpet stain removers can be a lifesaver. Many of us have been there, and witnessed that moment when time slows down and a glass of red wine tumbles and splashes across your light carpet.

Wood stain adds a layer of beauty and protection to decks, fences, and exterior doors. And staining wood is a perfectly doable DIY project. But just because you can take on the task yourself doesn ...

So, unless you exclusively wear army fatigues or you've based your wardrobe around mission brown, you're going to have some stubborn stains gracing your laundry. Pre-wash stain remover sprays are an ...

Oil or grease splatter on your top while cooking? Luckily, you don't need to throw out your clothes -- not with our handy stain removal tips, which use simple household items you probably already ...

3 Graduate School of Biomedical Sciences at Icahn School of Medicine at Mount Sinai, New York, USA Objective Advanced hepatocellular carcinoma (HCC) is a lethal malignancy with limited treatment ...

Ten percent of the samples were saved for immunoblotting. The other 90% of samples were separated by SDS-PAGE, visualized by colloidal coomassie blue staining, destained and subjected to mass ...

Histopathologic examination of the specimen led to the diagnosis of primary cardiac undifferentiated sarcoma, after exclusion of an intimal sarcoma in the absence of MDM2 gene amplification (18). Post ...