With the newly completed OT-101 and IL-2 Phase 1 trial, Oncotelic is poised to begin further combination trials to determine the added efficacy of OT-101, IL-2, and CKIs in solid tumors such as lung ...

Scientists at deCODE genetics/Amgen have identified associations between bipolar disorder and rare loss-of-function variants ...

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

TB is a result of complex interplay between M.tb and human immune cells. While current research can explain why TB manifests ...

Spatial transcriptomic analysis identifies epithelium-macrophage crosstalk in endometriotic lesions - (https://www.cell.com/iscience/fulltext/S2589-0042 (25)00049-5) ...

Type 1, not type 2 diabetes, is autoimmune. There are other rarer autoimmune types. Learn about type 2 diabetes, immunity, ...

Enlivex recently reported positive interim six (6) months efficacy data from the first stage of its ongoing randomized, multi-country Phase I/II Allocetra™ trial in patients with moderate to severe ...

Researchers from Moffitt Cancer Center have found a new way to boost cancer immunotherapy by targeting a protein called ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

A new review article published in Genes & Diseases sheds light on the complex molecular mechanisms through which tumor-infiltrating immune cells regulate endometrial carcinoma (EC). As one of the most ...

State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300350, People’s Republic of China College of Pharmacy, Nankai University, Tianjin 300350, People’s Republic of China ...

We identified a ‘TNF + PGE2’ (TP) gene expression signature that is enriched in RA synovial macrophage subsets and includes genes in pathogenic IL-1, Notch and neutrophil chemokine pathways. A similar ...