This trait garnered the attention of researchers who developed therapies to leverage macrophages’ abilities. 1 There are three different macrophage types, naïve (M0), antitumor (M1), and protumor (M2) ...

Macrophages, a type of white blood cell, adjust their molecular signaling patterns immediately after an infection, the ...

They found that macrophages expressing Gpnmb genes, which have historically been described as "pro-fibrotic" macrophages, were found in both types of lung injury, indicating that they may not be ...

The researchers also discovered that when these cells, called macrophages, eat live bacteria it triggers an inflammation response. But when they eat dead bacteria it doesn't. "When phagocytic ...

A recent study published in Engineering has shed new light on the mechanisms underlying the metastasis of head and neck squamous cell carcinoma (HNSCC). The research identified enolase 2 (ENO2), a ...

A new study published in Engineering has identified enolase 2 (ENO2) as a key factor in the lymphatic metastasis of head and ...

leveraging the natural role of macrophages to initiate a multi-faceted innate and adaptive anti-tumor response. The company’s lead CAR-M program, CT-0508, will soon enter phase 1 testing ...

Inflammatory processes are the body’s defence against local damage and disease. Inflammation involves the influx into organs of immune cells (white blood cells) from the blood. These cells deal with ...