Neurona Therapeutics has circled up $102 million to push its off-the-shelf cell therapy for epilepsy through phase 3 testing.

In her mind, a macrophage-focused therapy could take different forms—cell therapy delivering the anti-inflammatory macrophages themselves, delivery of products derived from macrophages ...

A new review published in Genes & Diseases highlights macrophage-targeted therapy as a promising frontier in cardiac regeneration and myocardial repair. The findings underscore the critical role ...

CAR-M is an individualized therapy that begins with isolation of ... dendritic cells (DCs), and repolarizing tumor-associated macrophages (TAMs) toward an M1 phenotype. In addition to direct ...

Temporomandibular joint (TMJ) osteoarthritis is a degenerative, debilitating and progressive disease, the second most common musculoskeletal ...

New methods for deriving macrophages from induced pluripotent stem cells are easier to scale and provide more clinically ...

After a year of stripping back its head count and pipeline, Carisma Therapeutics is now cutting down to the bone and laying ...

The macrophages also showcased morphological changes. “Looking at the world of cancer immunology and cell therapy, it is largely driven by biology. However, in addition to the biology of the cell, it ...

Researchers have found a new way to boost cancer immunotherapy by targeting a protein called macrophage receptor ... of immunotherapy known as anti-CTLA4 therapy, significantly enhances tumor ...

Bregenholt hopes that with this approach Macrophage, and its lead product MPL5821, could help pharma to overcome some of the issues that still dog checkpoint inhibitor therapy. While these drugs ...

Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing ...