CAR-M is an individualized therapy that begins with isolation of ... dendritic cells (DCs), and repolarizing tumor-associated macrophages (TAMs) toward an M1 phenotype. In addition to direct ...

A new review published in Genes & Diseases highlights macrophage-targeted therapy as a promising frontier in cardiac regeneration and myocardial repair. The findings underscore the critical role ...

Neurona Therapeutics has circled up $102 million to push its off-the-shelf cell therapy for epilepsy through phase 3 testing.

This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

Bregenholt hopes that with this approach Macrophage, and its lead product MPL5821, could help pharma to overcome some of the issues that still dog checkpoint inhibitor therapy. While these drugs ...

NESS-ZIONA, Israel I April 03, 2025 I Enlivex Therapeutics Ltd. (Nasdaq: ENLV, the “Company” or “Enlivex”), a clinical-stage macrophage reprogramming ...

Researchers have found a new way to boost cancer immunotherapy by targeting a protein called macrophage receptor ... of immunotherapy known as anti-CTLA4 therapy, significantly enhances tumor ...

The macrophages also showcased morphological changes. “Looking at the world of cancer immunology and cell therapy, it is largely driven by biology. However, in addition to the biology of the cell, it ...

Many other signals (both secreted chemicals and cell-cell surface interactions) also control the outcome of interaction between macrophages and T cells. These may be important targets for medical ...

A recent study published in Engineering has shed new light on the mechanisms underlying the metastasis of head and neck squamous cell carcinoma (HNSCC). The research identified enolase 2 (ENO2), a ...