Research led by Children's Hospital of Fudan University in China has found that a gene called pancreatic progenitor cell ...

or sometimes by switching off the gene altogether to see what happens if it doesn’t work (these are called knockout mice, and they’re a staple of medical lab research). In 2013, researchers in ...

The team also examined mice with a knocked out of the NRF2 gene, which is responsible for regulating redox balance. In these ...

The team used RNP-mediated knockout, multiplex precision genome editing and homology directed repair to modify the seven genes used for the final mice. "We've pushed the boundaries of genetic ...

The Ca2+ stored in the cellular endoplasmic reticulum (ER) plays a crucial role in protein folding and lipid transfer, and its impairment leads to cellular ER stress. When chronic cellular ER stress ...

Atopic dermatitis is an allergy affecting approximately 10% of the Japanese population, with symptoms closely related to ...

They then combined three editing technologies to edit the mouse genome—RNP-mediated knockout, multiplex precision genome editing, and precision homology-directed repair. They used these methods ...

After an intense study of the mammoth's genetic code, scientists have engineered 'woolly' mice with altered fur thickness, color, and texture to recreate the extinct elephant's adaptations to the cold ...