They cloned large fragments of human chromosomes into a mitotically stable human minichromosome using Cre/LoxP-mediated translocation and telomere-directed truncation of the chromosome fragments ...

In the mid-1970s, Elizabeth Blackburn, who was working as a postdoctoral associate in Joseph Gall's laboratory, set out to determine the telomere sequences of a minichromosome that contained the ...