Early embryonic cell polarity and lineage differentiation, which are vital to implantation, and continued embryonic growth climax with the onset of blastocyst formation. These processes are ...

Mosaic Down syndrome is a variant of Down syndrome. Down syndrome is a congenital (present at birth) genetic condition that occurs when a person has three copies of chromosome 21 instead of two (the ...

High-quality blastocysts with normal chromosomes tested by PGT would be firstly recommended to thaw and transfer. If there was no euploid embryo with patients, mosaic embryos with mosaicism <30% could ...

This retrospective cohort study aims to analyze the correlation of time-lapse (TL)-based variables and numeric blastocyst morphological scores (TLBMSs) with different mosaic levels. In total, 918 ...

In mammals, the first cellular differentiation is the segregation of trophectoderm and inner cell mass. The trophectoderm, which comprises the polarized outer surface of the blastocyst, will mainly ...

Embryonic polarity of invertebrates, amphibians and fish is specified largely by maternal determinants, which fixes cell fates early in development. In contrast, amniote embryos remain plastic and can ...