By analysing the relative proportions of duplicated and non-duplicated mutations, the authors could estimate when these trisomies arose. For example, in one person with gastric cancer, trisomy of ...

Hemophilia, a rare inherited bleeding disorder, is primarily caused by mutations in specific genes that impair the body’s ...

DNA contains genes that carry instructions for the manufacture of a protein. If a mutation occurs in a gene that results in a change to the sequence of DNA bases, then the structure of the protein ...

However, changes in the genome do occur. These are known as mutations. Mutations can have two results: no protein is expressed an altered protein is expressed Some mutations can affect a few bases ...

Host-parasite interactions are a famous example of this sort of situation ... If negative selection is too weak to remove harmful mutations, then deleterious mutation accumulation will occur ...

The study found that mutations to VPS35, a key player in this pathway, can prevent chemotherapy-induced cell death. These results could help pinpoint treatment-resistant tumors. Investigators at ...

RIKEN researchers have demonstrated the protective effects of a specific genetic mutation against Alzheimer's disease in animals for the first time. This could eventually lead to the development of ...