RECENTLY, metronidazole (‘Flagyl’) has been used in the treatment of alcoholism 1 and it has been suggested that it might inhibit alcohol dehydrogenase 2. We wish to present evidence to shed ...

Looking to boost your NAD+ levels but would like a few extra perks at the same time? Try Coutihot’s NADH 50 mg Plus CoQ10 200mg supplements. These super-charged pills contain 50mg nicotinamide ...

Scientists have discovered that the enzyme BbLDH is crucial for the survival and infectivity of the Lyme disease bacterium Borrelia burgdorferi. This finding opens the door to targeted treatments for ...

burgdorferi does not use thiamin as a cofactor and instead relies on lactate dehydrogenase (BbLDH) to convert pyruvate to lactate to balance the NADH/NAD+ ratio, which has not been reported in any ...

Mitochondrial-encoded NADH dehydrogenase 6 (MT-ND6) and Annexin A1 (ANXA1), as mitochondrial damage-associated molecular patterns (mtDAMPs) agonist and endogenous agonist of FPR1 respectively, ...

We also compare our results to a recently published structure of a related [NiFe] hydrogenase with a similar arrangement of cofactors around the NADH-binding site (Feng et al., 2022).

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is one such enzyme. It catalyzes the conversion of glyceraldehyde 3-phosphate to glycerate-1, 3-biphosphate, and results in production of NADH. The ...

Photosynthesis, or the conversion of light energy into chemical energy, is a process that powers almost all life on Earth. Plants and certain bacteria share similar processes to perform photosynthesis ...