The NADPH oxidase family (NOXs) are multisubunit transmembrane enzyme complexes involved in the generation of redox signals. Studies have shown that NOXs are highly expressed in the heart and are ...

Division of Environment and Sustainability, the Hong Kong University of Science and Technology, Hong Kong 999077, China Division of Emerging Interdisciplinary Areas, the Hong Kong University of ...

A Rac GTPase–regulated multiprotein NADPH oxidase is critical for the formation of reactive oxygen species (ROS) in phagocytic leukocytes and other nonphagocytic cells. NADPH oxidase reduces ...

Nrf2 also activates NADPH oxidases (NOX), NAD(P)H quinone dehydrogenase 1 (NQO1), heme oxygenase 1 (HO1), aldosterone reductases (AKRS), which all contribute to the production of ROS, resulting in ...